Our laboratory is interested in understanding the mechanisms underlying metastasis, the spread of tumor cells throughout the body. We are particularly involved in studying the role of the extracellular matrix, a fibrillar meshwork of proteins that surrounds both normal and tumor cells. more >>

Actin filamant bundles in cultured smooth muscle cells. Photo credit: Kwabena Badu-Nkansah
Focal contacts (yellow) and actin filament bundles (purple) in cultured endothelial cells. Photo credit: Kwabena Badu-Nkansah
Pericytes (red) surrounding blood vessels (blue).. Photo credit: Chris Turner, Kwabena Badu-Nkansah
Fibronectin matrix on cultured cells. Photo credit: Richard Hynes
Angiogenic sprouting into brain parenchyma. Photo credit: Joseph McCarty
Actin filamant bundles in cultured cells. Photo credit: Richard Hynes
Mouse eye in cross section. Photo credit: Joseph McCarty